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Showing all 19 items for (author: shoichet & bk)

EMDB-29898:
Cannabinoid receptor 1-Gi complex with novel ligand
Method: single particle / : Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, O'Brien ES, Krishna Kumar K, Makriyannis M, Basbaum AI, Shoichet BK

EMDB-26160:
Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl
Method: single particle / : Singh I, Seth A

EMDB-27752:
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-27753:
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-27754:
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-32331:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y

EMDB-32342:
Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist
Method: single particle / : Xu J, Fink EA, Shoichet BK, Du Y

EMDB-26597:
CryoEM structure of Go-coupled 5-HT5AR in complex with 5-CT
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-26598:
CryoEM structure of Go-coupled 5-HT5AR in complex with Lisuride
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-26599:
CryoEM structure of Go-coupled 5-HT5AR in complex with Methylergometrine
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-24378:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G

EMDB-24896:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL

EMDB-24897:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL

EMDB-24898:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL

EMDB-24899:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL

EMDB-24900:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Method: single particle / : Cao C, Fay JF, Gumpper RH, Roth BL

EMDB-21669:
HTR2A bound to 25-CN-NBOH in complex with a mini-Galpha-q protein, beta/gamma subunits and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Skiniotis G, Roth B, Kim K, Panova O

EMDB-0606:
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837
Method: single particle / : Zhang Z, Liu F

EMDB-0611:
Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR)
Method: single particle / : Liu F, Zhang Z, Chen J, Levit A, Shoichet B

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

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Related info.:Yorodumi Speices / Aug 12, 2020. Covid-19 info

External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

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